Pancreatin replaces digestive enzymes in patients with pancreatic disorders

Lipase determination at Nordmark
Lipase determination at Nordmark

Pancreatin is a mixture of digestive enzymes, obtained from porcine pancreas glands. Its main ingredients are lipase, amylase and various proteases. The enzyme pattern of porcine pancreatin displays substantial consistency to human pancreas secretions. This makes pancreatin exceptionally suitable for use in medicinal products designed to replace human digestive enzymes decreased by pancreatic disorder. A great deal of experience and utilisation of state-of-the-art technologies are required to manufacture such a complex enzyme product.

Product characteristics of pancreatin powder and pellets

Nordmark’s pancreatin is obtained from the pancreas’ of pigs from certified abattoirs. Our expertise, built over more than 50 years of pancreatin production, guarantees the highest possible level of quality for our products. We produce pancreatin mixtures with diverse levels of enzyme activity to meet customer demands for different drug strengths, based on defined activities of the lead enzyme lipase. We supply the active pharmaceutical ingredient pancreatin in powder and pellet form.

Pancreatin powder

Pancreatin powder
Pancreatin powder

Due to our special manufacturing process Nordmark’s pancreatin powder has outstanding application properties. It is differentiated by excellent free-flow properties and a high bulk density. The material can be pressed in high performance direct compression tablet presses after the addition of tableting adjuvant. We deliver diverse powder product qualities according to customer specifications and in accordance with Ph. Eur. or USP, as required.

Pancreatin pellets

Coated pancreatin pellets
Coated pancreatin pellets

Since the core of our pancreatin pellets is free of any additional adjuvants, they consist 100% of active pharmaceutical ingredient. Consequently, very high specific enzymatic activity can be reached with these pellets, permitting the production of pancreatin drugs in small, patient-friendly capsule sizes. We deliver diverse pellet product qualities according to customer specifications and in accordance with Ph. Eur. or USP, as required.

Pancreatin Info Gallery

From drug substance to drug product: Pancreatin production at Nordmark