Bacterial Lipase (BaLi)
Within the scope of the BaLi development project, a recombinant lipase obtained from the fermentation of bacteria is purified from the culture supernatant under GMP conditions. This purified enzyme is tested in clinical trials with patients suffering from the failure or impairment of the pancreatic digestive function (exocrine pancreatic insufficiency, EPI). Read more about it here.
In the newly built biocenter at Nordmark Arzneimittel GmbH & Co. KG, Ancrod is being isolated as an active substance from the venom of the Malayan Pit Viper (Calloselasma rhodostoma). Ancrod is a fibrinogen splitting enzyme that may be therapeutically significant in a number of indications, as it lowers the fibrinogen level in blood, leading to a reduction of blood viscosity. Read more about it here.
Pepsin Ph. Eur.
The extract containing the protease pepsin is obtained from porcine gastric mucosa. This extract is then used as an active pharmaceutical ingredient in drugs designed for the treatment of stomach disorders. We process the extract into a proprietary Nordmark drug called Enzynorm® f.